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As one of the four chronic diseases with the highest fatality rate, chronic obstructive pulmonary disease has a gradual progression from mild to severe. When the disease progresses to a certain level, it is necessary to use a non-invasive ventilator to assist ventilation, but how to quantify this level

Type II respiratory failure requires a ventilator

The lung function of patients with COPD will gradually decline over time. COPD may have no symptoms at the beginning, but will become more serious as it develops. Generally, it first develops to type 1 respiratory failure and type 1 respiratory failure. There is only hypoxia, but there is no carbon dioxide retention problem. At this stage, the main problem of the patient is hypoxia, so at this stage, home oxygen therapy is mainly used, which is what we commonly call home oxygen generator

When developing from type 1 to type 2 respiratory failure, the patient will not only suffer from hypoxia but also carbon dioxide retention. This is because the small airways become more and more blocked with the development, and the gas exchange capacity is further reduced. Excess carbon dioxide is difficult to excrete from the body, and it will cause carbon dioxide retention in the long term. At this stage, ventilator treatment is needed.

How to judge whether it is carbon dioxide retention

The best way for carbon dioxide retention is to go to the hospital to do an arterial blood gas analysis. Through the arterial blood gas analysis, you can know the oxygen partial pressure, carbon dioxide partial pressure and other indicators. Generally, the carbon dioxide partial pressure exceeds 45 to be abnormal.

How does the ventilator reduce the problem of carbon dioxide retention

The ventilator provides continuous positive pressure ventilation to the patient’s airway to increase the patient’s minute ventilation and realize the smooth exchange of patient’s gas. Because the small airway is not clear, the chronic obstructive pulmonary disease patient is only poorly oxygenated in the early stage and develops to the later stage. Not only is the oxygenation poor, but it also leads to a further decrease in ventilation. The decrease in ventilation will not only aggravate the problem of hypoxia, but also lead to poor gas exchange and difficult to discharge exhaust gas from the body.

The function of the ventilator is to increase the patient’s ventilation. The breathing opportunity increases the pressure when the patient inhales, helping the patient to inhale more gas. When exhaling, the breathing opportunity reduces the pressure and uses the pressure difference between the lungs and the outside to help The patient discharges exhaust gas from the body, so that the ventilation rate increases, so that too much carbon dioxide will not accumulate in the body. This is the principle that the ventilator helps the patient reduce the risk of carbon dioxide retention.

The ventilator can not only reduce the patient’s carbon dioxide partial pressure, but also improve the patient’s oxygenation. When the patient is in the type II respiratory failure period, it is not recommended to let the flow rate exceed 2L/min in general oxygen therapy, because the patient’s ventilation ability at this stage is not good, inhaling too much oxygen will increase the risk of carbon dioxide retention, so it is at this stage. Low flow oxygen inhalation, low flow oxygen inhalation is not good for improving oxygen consolidation. Therefore, at this stage, it is generally recommended to increase the oxygen flow while using a ventilator. It is recommended to purchase an oxygen generator of no less than 5L for family use of oxygen generators. When using a ventilator combined with an oxygen generator, because the ventilator increases the ventilation and the ventilator dilutes a part of the oxygen concentration, high-flow oxygen inhalation does not cause the risk of carbon dioxide retention.

After many data control experiments, Guangzhou Hepuler Ventilator R&D Center confirmed that home ventilator treatment can reduce the respiratory load of patients, reduce the number of hospitalizations for acute attacks, and improve the quality of life of COPD patients.

The constant volume function in the 8-series ventilator developed by Hepuler can set the target tidal volume so that patients with COPD can always maintain sufficient minute ventilation to meet the gas exchange needs of patients for a long time and improve carbon dioxide. Retention, etc.